Pyrimidines And Derivatives

Aromatic organic compounds that consist of an aromatic six-membered ring containing two non-adjacent nitrogen atoms and four carbon atoms; includes compounds derived from pyrimidines.

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1,816 – 1,830 of 5,971 results

1,816

Ambeed AMBEED

5000886370 VONOPRAZAN 250MG

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1,817

Ambeed AMBEED

5000886462 ETHYL 6-CHLOROIMIDAZO12- 5G

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1,818

Axxora LLC AXXORA LLC

NC3939696 PPPA 2 5 PA

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1,819

Apexbio Technology LLC Terazosin HCl 70024-40-7 250mg

Terazosin hydrochloride (CAS 70024-40-7) is a selective antagonist of alpha1-adrenergic receptors By inhibiting these receptors terazosin induces relaxation of smooth muscle in the prostate and bladder neck thereby reducing urinary outflow resistance It is widely utilized in biomedical research to study the modulation of alpha1-adrenergic signaling pathways and the pathophysiology of lower urinary tract symptoms particularly in the context of benign prostatic hyperplasia (BPH) Its mechanism supports investigations into autonomic regulation of smooth muscle function and the pharmacological management of urological disorders

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1,820

eMolecules Ambeed VcMMAE 250mg 526389978 A153774 0 000 646502-53-6 MFCD25372036 1316 650 C68H105N11O15

Ambeed VcMMAE 250mg 526389978 A153774 0 000 646502-53-6 MFCD25372036 1316 650 C68H105N11O15

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1,821

Medchemexpress LLC Nervonic acid | 506-37-6 | 250 MG

Nervonic acid, also known as Selacholeic acid, is a monounsaturated fatty acid. It is recognized for its oral activity and its ability to exert anti-inflammatory effects by inhibiting NF-κB signaling pathways. This compound naturally occurs in human milk and plays a significant role in the development of white matter.

Monounsaturated fatty acid
Exhibits oral activity
Demonstrates anti-inflammatory activity
Inhibits NF-κB signaling
Crucial for white matter development
Naturally present in human milk

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1,822

Medchemexpress LLC Pyrimido[4,5-d]pyrimidin-2(1H)-one, 7-[[2-methoxy-4-(1-methyl-4-piperidinyl)phenyl]amino]- | 1936529-65-5 | 99.8% | 600.11 | C32H34ClN7O3 | 250 MG

YKL-05-099 is a small-molecule salt-inducible kinase (SIK) inhibitor used as a research tool in biochemical and cell-based studies. It exhibits high potency for SIK1 and SIK3, with reported IC50 values in the low nanomolar range, and is applied for kinase assays, signaling investigations, and target validation. The compound has a molecular weight of 600.11 and a reported purity of 99.76%.

Potent inhibition of SIK1 and SIK3 (IC50 ≈ 10 and 30 nM, respectively).
Moderate activity against SIK2 (IC50 ≈ 40 nM).
High chemical purity (99.76%).
Suitable for biochemical kinase assays and cell-based signaling studies.
Provided as a solid research compound for laboratory use.

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1,823

Medchemexpress LLC TCO-PNB ester | 1438415-89-4 | 98.5% | C15H17NO5 | 25 MG

TCO-PNB ester is an amine-reactive building block used for the modification of amine-containing molecules. It contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.

Amine-reactive building block for modification of amine-containing molecules.
The TCO group allows for iEDDA reaction with Tetrazine-containing molecules.

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1,824

Medchemexpress LLC Ethyl β-carboline-3-carboxylate | 74214-62-3 | MFCD00009730 | 99.8% | C14H12N2O2 | 10MG

Ethyl β-carboline-3-carboxylate is a β-carboline derivative that functions as a ligand and short-acting antagonist at benzodiazepine receptors. It is used in preclinical research to probe benzodiazepine receptor pharmacology and to study interactions with diazepam, including modulation of cerebellar cGMP levels.

Ligand and short-acting antagonist of benzodiazepine receptors.
Useful for preclinical studies of benzodiazepine pharmacology and receptor modulation.
Demonstrated interaction with diazepam affecting cerebellar cGMP levels.
High purity (99.75%) suitable for research applications.
Solid, off-white to light yellow appearance for easy handling.
Storage: sealed and away from moisture; in solvent store at -80°C up to 6 months or -20°C up to 1 month.

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1,825

Medchemexpress LLC Arborinine | 5489-57-6 | 99.9% | 250 MG

Arborinine is a potent and orally active LSD1 inhibitor, demonstrating significant antitumor activity. It operates by increasing the expression of H3K4me1/2, H3K9me1/2, and E-cad protein, while concurrently decreasing the expression of UBE2O protein levels. Arborinine has been shown to induce cell cycle arrest at the S phase and inhibit cell apoptosis. Its antiproliferative effects have been observed in various cell lines, including 7860, A498, 769P, Caki1, and OSRC2 cells. Furthermore, in in vivo studies, Arborinine exhibited antitumor activity in mouse models by inhibiting tumor growth without affecting body weight.

Potent LSD1 inhibitor.
Orally active.
Modulates gene expression: increases the expression of H3K4me1/2, H3K9me1/2, and E-cad protein.
Decreases UBE2O protein level.
Induces cell cycle arrest at the S phase.
Inhibits apoptosis.
Antitumor activity.

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1,826

Cambridge Isotope Laboratories Mono-(2-ethyl-5-carboxypentyl)phthalate (DEHP metabolite V) (13C4 99%) 100 ug/mL in MTBE 1 2 mL

Mono-(2-ethyl-5-carboxypentyl)phthalate (DEHP metabolite V) (13C4 99%) 100 ug/mL in MTBE 1 2 mL

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1,827

eMolecules 2757082-66-7 | ChemScene | (R)-4-Isopropyl-2-(pyrimidin-2-yl)-45-dihydrooxazole | 100mg | 632337594 | CS-0179438 | 191.234 | C10H13N3O

Medchem Express | gamma-DGG | 5mg | 446256079 | HY-100785 | 6729-55-1 | MFCD00063109 | 204.182 | C7H12N2O5

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>

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1,828

eMolecules 32005-36-0 | Bis(dibenzylideneacetone)palladium | AA Blocks LLC | MFCD00051942 | 575.020 | C34H28O2Pd | 0.000 | [Pd].O=C(\C=C\c1ccccc1)/C=C/c1ccccc1.O=C(\C=C\c1ccccc1)/C=C/c1ccccc1 | 250mg | 705598418

Bis(dibenzylideneacetone)palladium | AA Blocks LLC | 32005-36-0 | MFCD00051942 | 575.020 | C34H28O2Pd | 0.000 | [Pd].O=C(\C=C\c1ccccc1)/C=C/c1ccccc1.O=C(\C=C\c1ccccc1)/C=C/c1ccccc1 | 250mg | 705598418

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1,829

Medchemexpress LLC Mitochonic acid 5 | 1354707-41-7 | 99.60% | 329.30 | 25 MG

Mitochonic acid 5 (MA-5) is a compound that binds to mitochondria and helps alleviate damage to renal tubules and cardiac myocytes. It modulates mitochondrial ATP synthesis, protecting mitochondrial function by regulating energy metabolism and reducing mitochondrial oxidative stress.

Binds mitochondria and ameliorates renal tubular and cardiac myocyte damage.
Modulates mitochondrial ATP synthesis.
Protects mitochondrial function by regulating energy metabolism and reducing mitochondrial oxidative stress.
Dose-dependently inhibits TNFα-induced cell viability decrease in microglia.
Improves renal function in ischemia-reperfusion injury and cisplatin-induced nephropathy models.

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1,830

Medchemexpress LLC 2,4-Dichlorobenzenediazonium (tetrafluoroborate) | 21872-70-8 | HY-D0898 | ≥95.0% | 250 MG

2,4-Dichlorobenzenediazonium (tetrafluoroborate) | 21872-70-8 | HY-D0898 | ≥95.0% | 250 MG

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Pyrimidines And Derivatives

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Axxora LLC AXXORA LLC Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Terazosin HCl 70024-40-7 250mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nervonic acid | 506-37-6 | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pyrimido[4,5-d]pyrimidin-2(1H)-one, 7-[[2-methoxy-4-(1-methyl-4-piperidinyl)phenyl]amino]- | 1936529-65-5 | 99.8% | 600.11 | C32H34ClN7O3 | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC TCO-PNB ester | 1438415-89-4 | 98.5% | C15H17NO5 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ethyl β-carboline-3-carboxylate | 74214-62-3 | MFCD00009730 | 99.8% | C14H12N2O2 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Arborinine | 5489-57-6 | 99.9% | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mitochonic acid 5 | 1354707-41-7 | 99.60% | 329.30 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2,4-Dichlorobenzenediazonium (tetrafluoroborate) | 21872-70-8 | HY-D0898 | ≥95.0% | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More